Therefore increased viscosity can also be seen in polycythemia, thrombocytosis, leukemias. A simple method would be to break the fibrin clot with a tip and centrifuge the sample. If you face this problem with all your samples, check the expiry date of the batch of SST or clot activator sample collection tubes being used.Ģ) The viscosity of blood depends to a large degree upon the size and concentration of the particles in suspension, principally the red blood cells and the other cellular components. Prevent early centrifugation before the clotting process is incomplete. Prevented by proper clotting followed by centrifugation. Let’s see what are the different reasons for viscosity of fluids in a laboratory.ġ)Persistence of fibrin clot (due to improper coagulation). Hyperviscosity may be manifested by nasal bleeding, blurred vision, headaches, dizziness, nystagmus, deafness, diplopia, ataxia, paresthesias, or congestive heart failure. Many variables can affect the viscosity of protein solutions, such as surface charge, molecule shape, solvent viscosity, pH, ionic strength, temperature, and shear rate. What is viscosity ? Viscosity is a measure of a fluid's resistance to flow.A fluid with high viscosity resists motion because its molecular makeup due to internal friction I will try to outline in brief on how to proceed and what are the considerations before proceeding with the same.
A common question that I get is how to proceed with viscous samples testing. They can be serum or body fluids.We are worried that viscous samples on autoanalyzers can lead to blocking of either pipettes or tubings.
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